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Complete Transcript:
Did you know that about 10% of people using Dupixent develop awful face and neck dermatitis?
This issue (more officially called Dupilumab Facial Redness (DFR)) wasn’t flagged during the randomized FDA trials, but has some dermatologists concerned because DFR can be incredibly severe, just as it was for one of my clients.
Since Dupixent is a biologic drug used by some with Eczema and Topical Steroid Withdrawal to ease symptoms, this new problem isn’t ideal.
Rather than just assume that the person has a sensitivity to Dupixent, new research is showing that this may be a different problem — Malasezzia hypersensitivity.
If you recall, Malasezzia is a fungal organism that normally lives in your skin’s microbiome.
It really shouldn’t be causing an issue like this, but something about the way that Dupixent interacts with your immune system along with a compromised skin barrier could play a role.
Here are the current papers discussing this topic so you have something to bring to your prescribing dermatologist so you can get the help you need if you are experiencing this!
SHOW NOTES:
• Facial + neck redness that occurs in about 10% of Dupixent users
• What current research on what may be driving this weird “side effect”
• Treatment options listed in currently published articles
• The blood test marker that could be helpful in getting a clear diagnosis
• What to do if YOU have face + neck redness from Dupixent
LINKS DISCUSSED IN THIS EPISODE:
• Topical Steroid Withdrawal-
• Healthy Skin Show ep. 173: Malassezia: The Bug Behind Many Fungal Skin Problems w/ Dr. Julie Greenberg-
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ABOUT JENNIFER FUGO, MS, CNS:
Jennifer Fugo, MS, LDN, CNS is a clinical nutritionist empowering women who’ve been failed by conventional medicine to beat chronic skin and unending gut challenges. Because she’s overcome a long history of gut issues and eczema, Jennifer has empathy and insight to help her clients discover missing pieces and create doable integrative plans.
She holds a Master’s degree in Human Nutrition from the University of Bridgeport and is a Licensed Dietitian-Nutritionist and Certified Nutrition Specialist. Her work has been featured on Dr. Oz, Reuters, Yahoo!, CNN, and many podcasts and summits. Jennifer is a faculty member of the LearnSkin platform, an Amazon best-selling author, and the host of the Healthy Skin Show.
FREE eGUIDE: Are you ready to identify the hidden root causes triggering your chronic skin rashes? Download my Skin Rash Root Cause Finder to get started:
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DISCLAIMER: Jennifer Fugo is a clinical nutritionist who offers health, wellness and nutritional information for educational purposes only. You should not rely on this information as a substitute for, nor does it replace professional medical advice, diagnosis, or treatment. It also does not create a client-practitioner relationship between yourself + Jennifer. If you have any concerns or questions about your health, you should consult with a physician or other health care professional first before making any changes. Do not disregard, avoid, or delay obtaining medical or health-related advice because of something you may have seen in these videos.
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#Dupixent #DupilumabFacialRedness #Malasezzia
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