Psoriasis, what is the cause? What are the symptoms? How is psoriasis treated? Find out more and new effective treatments that are now available.
What is it?
Psoriasis is a common, chronic inflammatory skin disease that is characterized by the formation of sharply demarcated, scaly, erythematous plaques. The plaques are most frequently found on the extensor surfaces (elbows and knees), the scalp, and the intergluteal cleft. Psoriasis can present at any age. However, the disease onset appears to peak around 20–30 years of age and again at 50–60 years of age.
Signs and Symptoms?
Psoriasis is characterized clinically by red and scaly plaques sharply demarcated from normal skin.
Psoriasis is associated with several comorbidities, including increased incidence of myocardial infarction, stroke, and death, particularly in patients with moderate-to-severe psoriasis.
Treatment
Stop smoking – research shows it seems to play a role in the onset of psoriasis. Follow a healthy diet.
Healthy BMI – might need to lose weight.
Treatments include topical therapy for mild disease; phototherapy and oral therapy, such as retinoids and immunomodulating agents; and targeted biologic therapies that have revolutionized treatment of psoriasis and psoriatic arthritis.
The latest biologic medications for psoriasis target T-cell immune pathways, and their ability to clear plaques underlines the importance of the T-cell pathways these medications target.
References:
Michael Kelly-Sell MDand Johann E. Gudjonsson MD, PhD Therapy for Severe Psoriasis, Chapter 1, 1-15
Bhutani, T., Liao, W., & Nakamura, M. (Eds.). (2018). Evidence-based psoriasis : diagnosis and treatment (Ser. Updates in clinical dermatology). Springer.
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Disclaimer: Information in this video is general in nature and any individual health concern should be discussed with a General Practitoner (GP).
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